Nick Mullens will start at quarterback on Sunday for the San Francisco 49ers in place of the injured Jimmy Garoppolo but won't have All-Pro tight end George Kittle as an option. Garoppolo didn't practice all week because of a high ankle sprain suffered last week but wasn't officially ruled out for this week's game against the New York Giants until Friday. Coach Kyle Shanahan also said Friday that Kittle will miss a second straight game after spraining his knee in the season opener.
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